Vered Stearns Selected Research

Aromatase Inhibitors

4/2024	Incorporation of emergent symptoms and genetic covariates improves prediction of aromatase inhibitor therapy discontinuation.
2/2024	Attempted replication of pharmacogenetic association of variants in PPP1R14C and CCDC148 with aromatase inhibitor-induced musculoskeletal symptoms.
1/2024	Polypharmacy, over-the-counter medications, and aromatase inhibitor adherence in early-stage breast cancer.
6/2023	Factors associated with weight gain in pre- and post-menopausal women receiving adjuvant endocrine therapy for breast cancer.
11/2022	Q-122 as a novel, non-hormonal, oral treatment for vasomotor symptoms in women taking tamoxifen or an aromatase inhibitor after breast cancer: a phase 2, randomised, double-blind, placebo-controlled trial.
10/2022	Genome-wide association study of aromatase inhibitor discontinuation due to musculoskeletal symptoms.
1/2021	Genome-wide association study of letrozole plasma concentrations identifies non-exonic variants that may affect CYP2A6 metabolic activity.
1/2021	Further Evidence That OPG rs2073618 Is Associated With Increased Risk of Musculoskeletal Symptoms in Patients Receiving Aromatase Inhibitors for Early Breast Cancer.
8/2019	Prospective evaluation of finger two-point discrimination and carpal tunnel syndrome among women with breast cancer receiving adjuvant aromatase inhibitor therapy.
1/2019	Effects of SLCO1B1 polymorphisms on plasma estrogen concentrations in women with breast cancer receiving aromatase inhibitors exemestane and letrozole.

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Vered Stearns Research Topics

Disease

171	Breast Neoplasms (Breast Cancer) 04/2024 - 04/2002
83	Neoplasms (Cancer) 02/2024 - 04/2002
20	Hot Flashes 01/2011 - 04/2002
16	Triple Negative Breast Neoplasms 02/2024 - 08/2009
10	Pathologic Complete Response 11/2023 - 02/2010
10	Pain (Aches) 06/2023 - 09/2008
5	Cardiovascular Diseases (Cardiovascular Disease) 03/2016 - 05/2003
4	Weight Loss (Weight Reduction) 01/2022 - 01/2017
4	Neoplasm Metastasis (Metastasis) 01/2022 - 07/2013
3	Disease Progression 01/2021 - 01/2018
3	Carcinogenesis 01/2020 - 07/2006
2	Inflammatory Breast Neoplasms 01/2024 - 04/2002
2	Weight Gain 06/2023 - 08/2012
2	Neutropenia 01/2022 - 06/2009
2	Brain Neoplasms (Brain Tumor) 04/2021 - 08/2014
2	Noninfiltrating Intraductal Carcinoma (DCIS) 01/2019 - 03/2009
2	Cardiotoxicity 01/2018 - 02/2010
2	Syndrome (Syndromes) 01/2016 - 08/2014
2	Hypersensitivity (Allergy) 10/2014 - 12/2009
2	Osteoporosis 04/2013 - 03/2011
2	Hematologic Neoplasms (Hematological Malignancy) 12/2012 - 03/2012

Drug/Important Bio-Agent (IBA)

54	Hormones (Hormone)IBA 04/2024 - 06/2003
38	Aromatase InhibitorsIBA 04/2024 - 07/2006
29	Tamoxifen FDA LinkGeneric 01/2023 - 12/2003
27	Biomarkers (Surrogate Marker)IBA 11/2023 - 11/2004
24	exemestane (Aromasin)FDA Link 01/2023 - 09/2008
21	Estrogen ReceptorsIBA 11/2023 - 12/2008
20	Letrozole (Femara)FDA LinkGeneric 10/2022 - 07/2006
17	Estrogens (Estrogen)FDA Link 01/2023 - 05/2003
11	Cytochrome P-450 CYP2D6 (CYP2D6)IBA 03/2012 - 12/2003
10	human ERBB2 proteinIBA 01/2022 - 01/2015
10	DNA (Deoxyribonucleic Acid)IBA 11/2017 - 03/2012
9	Anastrozole (Arimidex)FDA LinkGeneric 04/2024 - 12/2010
8	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2016 - 01/2003
7	Progesterone Receptors (Progesterone Receptor)IBA 01/2023 - 11/2009
7	Antidepressive Agents (Antidepressants)IBA 01/2011 - 05/2003
6	Trastuzumab (Herceptin)FDA Link 11/2023 - 02/2010
6	Cyclophosphamide (Cytoxan)FDA LinkGeneric 10/2014 - 03/2004
5	ametantrone (HAQ)IBA 04/2024 - 09/2008
5	entinostat (MS 275)IBA 02/2024 - 01/2016
5	Paclitaxel (Taxol)FDA LinkGeneric 01/2024 - 01/2003
5	PlatinumIBA 11/2023 - 06/2015
5	palbociclibIBA 01/2022 - 01/2018
5	Histone Deacetylase InhibitorsIBA 01/2022 - 01/2015
5	Gabapentin (Neurontin)FDA LinkGeneric 09/2009 - 05/2003
5	Paroxetine (Paxil)FDA LinkGeneric 01/2006 - 05/2003
5	Serotonin (5 Hydroxytryptamine)IBA 01/2006 - 04/2002
4	pertuzumabIBA 11/2023 - 01/2018
4	taxaneIBA 10/2022 - 08/2009
4	VaccinesIBA 10/2020 - 03/2004
4	Proteins (Proteins, Gene)FDA Link 01/2020 - 01/2003
4	Raloxifene Hydrochloride (Evista)FDA Link 09/2013 - 07/2006
4	SodiumIBA 07/2011 - 12/2004
3	RNA (Ribonucleic Acid)IBA 01/2024 - 05/2002
3	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 11/2023 - 01/2015
3	ErbB Receptors (EGF Receptor)IBA 01/2023 - 01/2015
3	Carboplatin (JM8)FDA LinkGeneric 01/2021 - 10/2011
3	CytokinesIBA 01/2020 - 02/2014
3	LipidsIBA 01/2020 - 12/2012
3	Vorinostat FDA Link 01/2018 - 07/2013
3	MethyltransferasesIBA 06/2017 - 12/2012
3	Estradiol (Delestrogen)FDA LinkGeneric 01/2017 - 06/2003
3	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 10/2014 - 03/2004
3	AndrogensIBA 10/2013 - 07/2004
3	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 09/2013 - 05/2006
3	Docetaxel (Taxotere)FDA Link 09/2012 - 06/2006
3	Selective Estrogen Receptor Modulators (SERM)IBA 01/2011 - 07/2006
3	EnzymesIBA 01/2011 - 01/2005
3	Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA 01/2006 - 12/2003
2	NivolumabIBA 02/2024 - 11/2021
2	IpilimumabIBA 02/2024 - 11/2021
2	beta-Aminoethyl Isothiourea (AET)IBA 06/2023 - 12/2020
2	Circulating Tumor DNAIBA 03/2023 - 06/2012
2	Immune Checkpoint InhibitorsIBA 01/2022 - 01/2020
2	Cyclin-Dependent Kinases (cdk Proteins)IBA 01/2022 - 12/2018
2	A-Form DNA (A-DNA)IBA 01/2022 - 06/2017
2	Methylnitrosourea (N-Methyl-N-nitrosourea)IBA 01/2019 - 10/2011
2	Estrone FDA Link 01/2017 - 02/2012
2	estrone sulfate (Evex)FDA Link 01/2017 - 02/2012
2	Transaminases (Aminotransferases)IBA 07/2015 - 05/2011
2	Albumin-Bound Paclitaxel FDA Link 01/2015 - 10/2011
2	salicylhydroxamic acid (SHAM)IBA 02/2014 - 02/2013
2	AnthracyclinesIBA 05/2013 - 08/2009
2	liposomal doxorubicin (Doxil)FDA Link 08/2012 - 10/2011
2	1-dodecylpyridoxal (PLD)IBA 08/2012 - 10/2011
2	4-hydroxy-N-desmethyltamoxifenIBA 03/2012 - 07/2006
2	Simvastatin (Zocor)FDA LinkGeneric 02/2012 - 01/2012

Therapy/Procedure

103	Therapeutics 02/2024 - 04/2002
34	Drug Therapy (Chemotherapy) 01/2024 - 01/2003
12	Neoadjuvant Therapy 03/2023 - 04/2002
6	Radiotherapy 01/2022 - 04/2002
6	Chemoprevention 09/2013 - 11/2004
5	Adjuvant Chemotherapy 01/2023 - 05/2006
4	Immunotherapy 01/2024 - 12/2009
4	Segmental Mastectomy (Lumpectomy) 01/2023 - 04/2002
4	Hypnosis (Mesmerism) 07/2010 - 07/2004
3	Precision Medicine 10/2021 - 01/2017
2	Mastectomy (Mammectomy) 06/2023 - 10/2014
2	Caloric Restriction 01/2022 - 01/2017
2	Duration of Therapy 10/2019 - 07/2006